• 1.

    Bloomfield CD, Archer KJ, Mrozek K, Lillington DM, Kaneko Y, Head DR, et al. 11q23 balanced chromosome aberrations in treatment-related myelodysplastic syndromes and acute leukemia: report from an international workshop. Genes Chromosomes Cancer. 2002;33:362–78. https://doi.org/10.1002/gcc.10046.

    Article 
    PubMed 

    Google Scholar 

  • 2.

    BH J, Gill Super NR, McCabe MJ, Thirman R, Larson MM, Le Beau, et al. Rearrangements of the MLL gene in therapy-related acute myeloid leukemia in patients previously treated with agents targeting DNA-topoisomerase I1. Blood. 1993;82:3705–11.

    Article 

    Google Scholar 

  • 3.

    Grimwade D, Hills RK, Moorman AV, Walker H, Chatters S, Goldstone AH, et al. Refinement of cytogenetic classification in acute myeloid leukemia: determination of prognostic significance of rare recurring chromosomal abnormalities among 5876 younger adult patients treated in the United Kingdom Medical Research Council trials. Blood. 2010;116:354–65. https://doi.org/10.1182/blood-2009-11-254441.

    CAS 
    Article 
    PubMed 

    Google Scholar 

  • 4.

    Gole B, Wiesmuller L. Leukemogenic rearrangements at the mixed lineage leukemia gene (MLL)-multiple rather than a single mechanism. Front Cell Dev Biol. 2015;3:41. https://doi.org/10.3389/fcell.2015.00041.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • 5.

    Dohner H, Estey E, Grimwade D, Amadori S, Appelbaum FR, Buchner T, et al. Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel. Blood. 2017;129:424–47. https://doi.org/10.1182/blood-2016-08-733196.

    CAS 
    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • 6.

    Goyama S, Yamamoto G, Shimabe M, Sato T, Ichikawa M, Ogawa S, et al. Evi-1 is a critical regulator for hematopoietic stem cells and transformed leukemic cells. Cell Stem Cell. 2008;3:207–20. https://doi.org/10.1016/j.stem.2008.06.002.

    CAS 
    Article 
    PubMed 

    Google Scholar 

  • 7.

    Barjesteh van Waalwijk van Doorn-Khosrovani S, Erpelinck C, van Putten WL, Valk PJ, van der Poel-van de Luytgaarde S, Hack R, et al. High EVI1 expression predicts poor survival in acute myeloid leukemia: a study of 319 de novo AML patients. Blood. 2003;101:837–45. https://doi.org/10.1182/blood-2002-05-1459.

    CAS 
    Article 
    PubMed 

    Google Scholar 

  • 8.

    Haas K, Kundi M, Sperr WR, Esterbauer H, Ludwig WD, Ratei R, et al. Expression and prognostic significance of different mRNA 5’-end variants of the oncogene EVI1 in 266 patients with de novo AML: EVI1 and MDS1/EVI1 overexpression both predict short remission duration. Genes Chromosomes Cancer. 2008;47:288–98. https://doi.org/10.1002/gcc.20532.

    CAS 
    Article 
    PubMed 

    Google Scholar 

  • 9.

    Groschel S, Lugthart S, Schlenk RF, Valk PJ, Eiwen K, Goudswaard C, et al. High EVI1 expression predicts outcome in younger adult patients with acute myeloid leukemia and is associated with distinct cytogenetic abnormalities. J Clin Oncol. 2010;28:2101–7. https://doi.org/10.1200/JCO.2009.26.0646.

    CAS 
    Article 
    PubMed 

    Google Scholar 

  • 10.

    Groschel S, Schlenk RF, Engelmann J, Rockova V, Teleanu V, Kuhn MW, et al. Deregulated expression of EVI1 defines a poor prognostic subset of MLL-rearranged acute myeloid leukemias: a study of the German-Austrian Acute Myeloid Leukemia Study Group and the Dutch-Belgian-Swiss HOVON/SAKK Cooperative Group. J Clin Oncol. 2013;31:95–103. https://doi.org/10.1200/JCO.2011.41.5505.

    Article 
    PubMed 

    Google Scholar 

  • 11.

    Matsuo H, Kajihara M, Tomizawa D, Watanabe T, Saito AM, Fujimoto J, et al. EVI1 overexpression is a poor prognostic factor in pediatric patients with mixed lineage leukemia-AF9 rearranged acute myeloid leukemia. Haematologica. 2014;99:e225–7. https://doi.org/10.3324/haematol.2014.107128.

    CAS 
    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • 12.

    Gordon MY, Blackett NM. Reconstruction of the hematopoietic system after stem cell transplantation. Cell Transplant. 1998;7:339–44.

    CAS 
    Article 

    Google Scholar 

  • 13.

    BB D, Cheson PA, Cassileth DR, Head CA, Schiffer JM, Bennett CD, et al. Report of the National Cancer Institute-Sponsored Workshop on definitions of diagnosis and response in acute myeloid leukemia. J Clin Oncol. 1990;8:813–9.

    Article 

    Google Scholar 

  • 14.

    Flowers MED, Kansu E, Sullivan KM. Pathophysiology and treatment of graft versus host disease. Hematol Oncol Clin North Am. 1999;13:1091–112.

    CAS 
    Article 

    Google Scholar 

  • 15.

    He X, Wang Q, Cen J, Qiu H, Sun A, Chen S. et al. Predictive value of high EVI1 expression in AML patients undergoing myeloablative allogeneic hematopoietic stem cell transplantation in first CR. Bone Marrow Transplant. 2016;51:921–7. https://doi.org/10.1038/bmt.2016.71.

    CAS 
    Article 
    PubMed 

    Google Scholar 

  • 16.

    Goemans BF, Zwaan CM, Miller M, Zimmermann M, Harlow A, Meshinchi S, et al. Mutations in KIT and RAS are frequent events in pediatric core-binding factor acute myeloid leukemia. Leukemia. 2005;19:1536–42. https://doi.org/10.1038/sj.leu.2403870.

    CAS 
    Article 
    PubMed 

    Google Scholar 

  • 17.

    Lavallee VP, Baccelli I, Krosl J, Wilhelm B, Barabe F, Gendron P, et al. The transcriptomic landscape and directed chemical interrogation of MLL-rearranged acute myeloid leukemias. Nat Genet. 2015;47:1030–7. https://doi.org/10.1038/ng.3371.

    CAS 
    Article 
    PubMed 

    Google Scholar 

  • 18.

    Grossmann V, Schnittger S, Poetzinger F, Kohlmann A, Stiel A, Eder C, et al. High incidence of RAS signalling pathway mutations in MLL-rearranged acute myeloid leukemia. Leukemia. 2013;27:1933–6. https://doi.org/10.1038/leu.2013.90.

    CAS 
    Article 
    PubMed 

    Google Scholar 

  • 19.

    Pigneux A, Labopin M, Maertens J, Cordonnier C, Volin L, Socie G, et al. Outcome of allogeneic hematopoietic stem-cell transplantation for adult patients with AML and 11q23/MLL rearrangement (MLL-r AML). Leukemia. 2015;29:2375–81. https://doi.org/10.1038/leu.2015.143.

    CAS 
    Article 
    PubMed 

    Google Scholar 

  • 20.

    Chen L, Chen W, Mysliwski M, Serio J, Ropa J, Abulwerdi FA, et al. Mutated Ptpn11 alters leukemic stem cell frequency and reduces the sensitivity of acute myeloid leukemia cells to Mcl1 inhibition. Leukemia. 2015;29:1290–300. https://doi.org/10.1038/leu.2015.18.

    CAS 
    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • 21.

    Libura M, Asnafi V, Tu A, Delabesse E, Tigaud I, Cymbalista F, et al. FLT3 and MLL intragenic abnormalities in AML reflect a common category of genotoxic stress. Blood. 2003;102:2198–204. https://doi.org/10.1182/blood-2003-01-0162.

    CAS 
    Article 
    PubMed 

    Google Scholar 

  • 22.

    Frohling S, Schlenk RF, Breitruck J, Benner A, Kreitmeier S, Tobis K, et al. Prognostic significance of activating FLT3 mutations in younger adults (16 to 60 years) with acute myeloid leukemia and normal cytogenetics: a study of the AML Study Group Ulm. Blood. 2002;100:4372–80. https://doi.org/10.1182/blood-2002-05-1440.

    CAS 
    Article 
    PubMed 

    Google Scholar 

  • 23.

    Jiang X, Bugno J, Hu C, Yang Y, Herold T, Q J. et al. Eradication of acute myeloid leukemia with FLT3 ligand-targeted miR-150 nanoparticles. Cancer Res. 2016;76:4470–80. https://doi.org/10.1158/0008-5472.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • 24.

    Zhu X, He F, Zeng H, Ling S, Chen A, Wang Y, et al. Identification of functional cooperative mutations of SETD2 in human acute leukemia. Nat Genet. 2014;46:287–93. https://doi.org/10.1038/ng.2894.

    CAS 
    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • 25.

    Wang Q, Cheng T. Evidences for mutations in the histone modifying gene SETD2 as critical drivers in leukemia development. Sci China Life Sci. 2014;57:944–6. https://doi.org/10.1007/s11427-014-4702-6.

    Article 
    PubMed 

    Google Scholar 

  • 26.

    Arai S, Yoshimi A, Shimabe M, Ichikawa M, Nakagawa M, Imai Y, et al. Evi-1 is a transcriptional target of mixed-lineage leukemia oncoproteins in hematopoietic stem cells. Blood. 2011;117:6304–14. https://doi.org/10.1182/blood-2009-07-234310.

    CAS 
    Article 
    PubMed 

    Google Scholar 

  • 27.

    Hidemasa Matsuo KY, Nakatani Kana, Kamikubo Yasuhiko, Tomizawa Daisuke, Taga Takashi, Nobutaka Kiyokawa. et al. Coexistence and prognostic significance of EVI1 expression and driver mutations in KMT2A-rearranged acute myeloid leukemia. Blood. 2019;134(Supplement_1):1409. https://doi.org/10.1182/blood-2019-124652.

    Article 

    Google Scholar 

  • 28.

    Gupta V, Tallman MS, He W, Logan BR, Copelan E, Gale RP, et al. Comparable survival after HLA-well-matched unrelated or matched sibling donor transplantation for acute myeloid leukemia in first remission with unfavorable cytogenetics at diagnosis. Blood. 2010;116:1839–48. https://doi.org/10.1182/blood-2010-04-278317.

    CAS 
    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • 29.

    Schuurhuis GJ, Heuser M, Freeman S, E M-CB, Buccisano F, Cloos J. et al. Minimal/measurable residual disease in AML: a consensus document from the European LeukemiaNet MRD Working Party. Blood. 2018;131:1275–91. https://doi.org/10.1182/blood-2017-09-801498.

    CAS 
    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • 30.

    Meyer C, Schneider B, Jakob S, Strehl S, Attarbaschi A, Schnittger S, et al. The MLL recombinome of acute leukemias. Leukemia. 2006;20:777–84. https://doi.org/10.1038/sj.leu.2404150.

    CAS 
    Article 
    PubMed 

    Google Scholar 

  • 31.

    Burmeister T, Marschalek R, Schneider B, Meyer C, Gokbuget N, Schwartz S, et al. Monitoring minimal residual disease by quantification of genomic chromosomal breakpoint sequences in acute leukemias with MLL aberrations. Leukemia. 2006;20:451–7. https://doi.org/10.1038/sj.leu.2404082.

    CAS 
    Article 
    PubMed 

    Google Scholar 



  • Source link

     
    1 2 3 ... 11 12 13

     

    Okinawa Flat Belly Tonic


    Discovery In The Weight Loss Community The Ancient Japanese Tonic That Melts 54 LBS Of Fat
    cns_image_0
    Introducing The Okinawa Flat Belly Tonic System , The Most Potent Fat-Cell Destroying Solution On The Planet. When You Take The Okinawa Flat Belly Tonic Before 10am Once A Day, Your Body Will Force Fat Cells To Melt, To Release Harmful Toxins And Shrink Your Belly.


     

    Kris Fondran's ShapeShifter Yoga


    A complete body shaping and fat loss program that works on your schedule
    cns_image_1
    Introducing a breakthrough program that melts away flab and reshapes your body in as little as one hour a week Get Your Sexiest Body Ever Without crunches, cardio, or ever setting foot in a gym


     

    New Female Fat Loss Offer.


    The number #1 Selling Fat Loss Solution For Women. Get Started today.
    cns_image_2
    Cinderella Solution system has a 2 step solution that will allow you to lose weight without engaging in boring, repetitive cardio and without giving up the carbs that everyone loves to eat.


     

    Smoothies for weight loss


    Know The Delicious Easy-To-Make Smoothies For Weight Loss And Incredible Health
    cns_image_3
    This Is NOT Just A Big Book Of Smoothie Recipes. You're Getting The Same Proven5-Week Weight Loss And Health Improvement Program I Share With My Private Clients. All the smoothies are given in a very specific sequence and frequency to maximize your results.


     

    Over 30 Hormone Solution


    Grab The Secret Of A 55 Year Old Mother of 3 Discovered The Over 30 Hormone Weight Loss Solution
    cns_image_4
    The only weight loss solution designed specifically for women over 30 that fixes your hormones that change as you age. Learn How a 55 Year Old Mother of Three Discovered The Over 30 Hormone Weight Loss Solution That Over 97% Of People Still Have No Idea Exists


     

    Fast weight loss


    This E-book Takes Readers Through A 10-step Process so They Can Quickly Lose All The Weight.
    cns_image_5
    Look Good Feel Great is a compilation of the most powerful weight loss strategies I've discovered over the years and that you can use right now to start losing weight fast.It compiles the most powerful weight-loss principlesused by the world's best fitness experts all together in one system.


     

    Natural weight loss


    A rapid and lasting weight loss system to have a desired body.
    cns_image_6
    The creator of Slimquest system, Biodun Ogunyemi has long been fascinated by the role that our subconsciousour unconscious mindhas on our decisions, our behaviours, and our lifestyles.The programme consists of 4 powerful sessions that you can get access to and download immediately.


     

    Weight Loss For Women


    Finally A ' foolproof ' way for women to lose weight
    cns_image_7
    Discover ONE surprisingly simple trick to BURN belly flab, LOSE stubborn fat, get HEALTH...and (best of all)... look good NAKED


     

    How to Get Skinny Fast


    Revealed... The Myth Of Restrictive Dieting and Long Term Weight Loss...
    cns_image_8
    Get The Cunning Body-Hack eBook That Will Change The Way You Look At Weight Loss Forever... It Will Activate Your Metabolic Response Through Hunger-Slashing and Burn 50% Of ALL Your Daily Calories From Your Stored Fat


     

    3 Weird Tricks For A Flat Belly


    Learn How to get lean in 21 days and stay that way forever...
    cns_image_9
    Fat Loss Fiesta by Ingrid Macher: 3 Weird Tricks for a Flat Belly Keep reading to discover... Why you absolutely MUST regularly cheat on your diet.. How to get lean in 21 days and stay that way forever.. and the Harvard University Mind-Body fat loss secret.


    1 2 3 ... 11 12 13

    LEAVE A REPLY

    Please enter your comment!
    Please enter your name here